Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p046 | (1) | SRF2015

Effect of Rhodobacter sphaeroides LPS on toll-like receptor 4 in bovine endometrial cells

Chotimanukul Sroisuda , Swangchan-Uthai Theerawat , Techakumphu Mongkol

Introduction: Endometritis is one of the most common reproductive diseases affected postpartum bovine uteri. Lipopolysaccharide (LPS) from Gram-negative bacteria is recognized by Toll-like receptor 4 (TLR4). Binding of LPS and TLR4 mediates the expression of proinflammatory cytokines and chemokines. The excessive inflammatory responses could be involved with endometrial damage.TLR4 antagonist Rhodobacter sphaeroides LPS (RsLPS), is a potent antagonist of LPS from path...